Professional experience and career objectives: In vivo pharmacologist with over 20 years experience supporting pharmaceutical discovery focused on cardiovascular and metabolic diseases. Highly skilled in animal metabolism with broad experience encompassing multiple species, models and techniques. •19 years experience in pharmaceutical drug discovery emphasizing in vivo characterization of novel agents to treat diabetes, dyslipidemia, hypertension and atherosclerosis •4 years experience in academia, working in a renal hypertension lab.
Skills and areas of expertise: •Direct supervision of 4 scientists •Pharmacology representative to project teams •New target proposals •Proven success in the pharmaceutical industry, contributing to 3 marketed products (Rezulin, Lipitor and Accupril), 5 First-in-Human trials and 11 clinical candidates
Current Employment
Principal Research Associate
Tanabe Research Laboratories USA, Inc.
(Pharmaceutical Industry) - United States
october 2008 - Today (1 year 1 month)
Senior in vivo biologist with primary responsibility for diabetes metabolism target proposals, validation and characterization. Study design, in vivo, analytical, statistical interpretation and presentation of data. Provide additional technical support for inflammation targets and PK studies
Former Employment
Senior Staff Scientist
Amylin Pharmaceuticals
(Pharmaceutical Industry) - United States
june 2007 - august 2008 (1 year 2 months)
Senior member of In Vivo Screening Group responsible for initiation of a new project team •Established screening paradigm, lead team meetings•Implemented primary in vivo screen •Generated key PK/PD correlation for lead peptide •Telemetry, OGTT, and DIO/osmotic pump implants• PI on AUP's
Senior Scientist
Pfizer, Inc.
(Pharmaceutical Industry) - United States
august 1990 - june 2007 (16 years 10 months)
Expert in rodent models of diabetes and dyslipidemia responsible for planning, implementation, and data interpretation, presentation of in vivo efficacy/metabolic studies. Direct management, scheduling and data review of in vivo/analytical team for dyslipidemia and diabetes projects. PI on 11 AUPs
Laboratory Manager/ Research Assistant II
University of Michigan
(Research) - United States
september 1985 - august 1990 (4 years 11 months)
•Rat kidney micropuncture assistant: surgery, micropipette/drug preparation, sample collection and assays •Performed rat lateral nephrectomies, dissection/ perfusion of rabbit renal tubules •Generated data leading to Accupril •Isolated glomeruli and renal tubules •Managed 4 work study students
Education
University of Michigan - Stephen M. Ross School of Business United States (Michigan)
, june 2006 - november 2007
credits toward Executive MBA, management
AALAS-American Association of Laboratory Animal Science United States (Michigan)
, september 1986 - june 2009
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